When one compares belt-driven linear modules and screw-driven systems, it becomes evident that some of its major differences lie in load capacity and precision.
Load Capacity:
Belt-driven linear modules usually operate with either lighter or moderately heavy loads, thus their load capacities tend to be generally lower than those of screw-driven systems. For these applications, they are an advantage given weight is not a major concern.
Conversely, screw-driven systems make good use of the advantage of higher load capacities. In fact, they are well suited to applications where loads are moved with heavy force and stability. The screw drive, with its mechanical advantage, permits handling much heavier weights and operating under tremendous stresses.
Precision:
Where precision is concerned, belt-driven linear modules give fair accuracy but can encounter backlash due to the elasticity of the belt, which may experience some slip with heavy loads and high speeds; it shines in such applications where speed is more important than ultra-precise positioning.
On the other hand, screw-driven systems are more accurate because of their direct mechanical connection between screw and nut, leading to a negligible backlash and constant placement. Since CNC machines and high-precision test instruments used this accuracy, they were best recommended for applications requiring very high precision.
As a general rule, there is a higher speed at which belt modules can move lighter loads, whereas screw modules provide optimal performance for high load applications with better precision. It then stands to reason that the best choice is required by the specific physical characteristics of the particular case at hand, plus generally speaking the automation task to be performed, such as speed, load, and precision.